Sorry for the long post, however... After doing a weekly backup of data to my external USB Hard disk. I 'stopped' the device, then unplugged it from my computer (it was using one of the front USB ports)A few seconds after doing that, the computer suddenly locked up and I had to resort to a hard reboot. After pressing the reset button, the computer just hung permanently on the ASUS POST splash screen and wouldn't go further, so I just pressed on the power button for 4 seconds to turn it off and waited a while then turned it back on again, but it still did the same thing, hung at the POST splash screen. Having another go at rebooting, I hit DEL Key to enter the BIOS setup, loaded the defaults and exited, now it wouldn't hang at the POST screen anymore and would boot into windows OK. However I found that none of my USB devices were working anymore nor even being recognized. After rebooting back into Windows and still discovering that none of the USB devices were being recognized nor working, I went into the device manager to see if any of the system USB drivers were stuffed. As far as I could see there were no Yellow exclamation marks and checking the properties of all of the USB entries stated that USB was enabled and were 'working properly'. I uninstalled each of them, rebooted and windows re-installed them (then asked and used the Motherboard CD to install the rest). Rebooted and still the devices weren't being recognized. The devices were still working Okay on the Other computers, so that rules out the problems with the peripherals themselves. Booted into Mandrake, and the same thing. Can't print (thinks it's offline). So I'm guessing the USB sub system of my motherboard is possibly fried. Also tried flashing it with the latest BIOS and resetting it to the default settings, still no go. Is there anything else I should do or check for, to verify that it is in fact a hardware fault with the Motherboard and not a software/driver fault, before taking my system back to the manufacturer? (currently still under warranty) P4P800 Motherbaord P4 3.0GHz HT Thanks for any assistance.