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My application runs fine for a long while then, all of a sudden my
it starts getting this error pointing to my ascx control in the call stack

Could not load file or assembly 'App_Web_ih1xlmmx, Version=0.0.0.0,
Culture=neutral, PublicKeyToken=null' or one of its dependencies. The system
cannot find the file specified.

Line where call stack is pointing just has a simple panel declaration
error points here-> <aspanel ID="MyPanel" runat="server>

I saw people posts on other forums that experience the same issue, and work
around it by putting blank space into file and saving it to trick asp.net
2.0 that file was updated and needs to be recompiled.

Does there exist ASP.NET 2.0 hot fix that deals with this issue?

Thanks,

How often is the error occurring? And is it always the same control?